I may have been last in my office to take up backpack usage. My Kate Spade Grace bag comfortably accommodates either a MacBook Air or a fancy camera along with normal handbag items, and gets compliments at every party (see what I did there? :-) But a MacBook pro, ah, not so much bigger or heavier is, cumulatively, burden and a strain on the bag, I fear. Adding a Hudson Large Backpack to my lineup has made commute after commute more comfortable, the weight of a laptop forgettable, in fact. Straps easily adjust, compartments and sleeves elegantly accommodate items for activities throughout a day. Maybe a change of clothes for a workout or a run? Absolutely! A colleague of mine carries a water bottle and handbag worth of items in hers in the pouch above the laptop pouch. She was my inspiration for this purchase! Capacious and trim, you'll love this backpack, and discover conveniences as you carry it!